Pair Name	Ginsenoside Rg3, Endostar
Disease Info	[ICD-11: 2C60]	Breast cancer		Investigative
Biological Phenomena	Induction-->Autophagy
Gene Regulation	Down-regulation	Expression	AKT1	hsa207
	Down-regulation	Expression	BECN1	hsa8678
	Down-regulation	Expression	MAPK8	hsa5599
	Down-regulation	Expression	MMP2	hsa4313
	Down-regulation	Expression	MMP9	hsa4318
	Down-regulation	Expression	MTOR	hsa2475
	Down-regulation	Expression	PIK3CA	hsa5290
	Down-regulation	Expression	SQSTM1	hsa8878
	Down-regulation	Expression	VEGFA	hsa7422
	Down-regulation	Expression	VEGFB	hsa7423
	Down-regulation	Expression	VEGFC	hsa7424
In Vivo Model	MCF-7 cells were inoculated under right mammary gland of female C57 mice.
Result	Endostar combined with ginsenoside Rg3 has stronger inhibiting effect on breast cancer tumor growth in tumor-bearing mice than single drug, and it can inhibit angiogenesis and cell invasion, and enhance cell autophagy.